发明名称 |
Methods of use of genes of pyridoxal 5'-phosphate biosynthesis in Bacillus subtilis: avirulent strains for vaccines, and methods for identification of antibacterial agents |
摘要 |
Methods and compositions comprising a pathogenic bacterial strain having a non-reverting mutation in a pdx gene encoding an enzyme involved in pyridoxal-5'-phosphate synthesis are provided, for use in vaccines, and methods for identification of inhibitors of the enzyme for use as an antibacterial agent are provided.
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申请公布号 |
US2005287169(A1) |
申请公布日期 |
2005.12.29 |
申请号 |
US20040869322 |
申请日期 |
2004.06.16 |
申请人 |
BELITSKY BORIS R |
发明人 |
BELITSKY BORIS R. |
分类号 |
A61K39/02;C07K14/32;C12N1/21;C12N9/10;C12N9/88;C12N15/74;(IPC1-7):A61K39/02 |
主分类号 |
A61K39/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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