PROCESS FOR THE PRODUCTION OF 9-CIS RETINOIC ACID

摘要

A new industrially applicable process for the production of 9-(Z)- retinoic acid is described which is characterized by the conversion of an alkali metal salt of 3-methyl-4-oxocrotonic acid with a C15- triphenyl-phosphonium salt. 9-(Z)-retinoic acid is a versatile compound for the treatment of numerous dermatological diseases.