PROCESSES FOR PRODUCTION OF OPTICALLY ACTIVE COMPOUNDS

摘要

A process for the production of optically active compounds (Ia) or (Ib) which comprises the first step of reacting a compound (II) with a compound (III) in the presence of a base to form a diastereomer mixture (I) and the second step of crystallizing an optically active compound (Ia) or (Ib) from the mixture (I) while making the mixture (I) undergo equilibrium epimerization in the presence of a base; and a process for the production of optically active compounds (IVa) or (IVb) by utilizing the above process.