The present invention relates to a process for the preparation of gabapentin and, more particularly, it relates to a precipitation process of gabapentin by acidification of an aqueous solution deriving from the Hofmann rearrangement of 1,1-cyclohexanediacetic acid monoamide.
申请公布号
WO2005092837(A3)
申请公布日期
2005.12.22
申请号
WO2005EP51297
申请日期
2005.03.21
申请人
ZAMBON GROUP S.P.A.;GIOVANETTI, ROBERTO;NICOLI, ANDREA;VERZINI, MASSIMO;SORIATO, GIORGIO;COTARCA, LIVIUS