<p>The present invention provides a method for determining the presence or amount of a metal-labelled species in a sample. In the method, the metal of the metal-labelled species in the sample is caused to form a soluble electrochemically-active complex which is then electrochemically measuring to provide an indication of the presence or amount of the metal-labelled species. The soluble electrochemically-active complex is stable relative to moieties present or potentially present in the sample which will form an insoluble and/or electrochemically-inactive complex with the metal. The metal-labelled species may be formed by the binding of an analyte to be detected with a metal-labelled binding partner, such as an antibody or antigen binding fragment thereof.</p>
申请公布号
WO2005121792(A1)
申请公布日期
2005.12.22
申请号
WO2005GB02248
申请日期
2005.06.07
申请人
INVERNESS MEDICAL SWITZERLAND GMBH;BIRCH, BRIAN, JEFFREY;FORSSTEN, CAMILLA, SOFIA;KABIL, ALENA;PORTER, ROBERT, ANDREW
发明人
BIRCH, BRIAN, JEFFREY;FORSSTEN, CAMILLA, SOFIA;KABIL, ALENA;PORTER, ROBERT, ANDREW