ENHANCEMENT OF AMPAKINE-INDUCED FACILITATION OF SYNAPTIC RESPONSES BY CHOLINESTERASE INHIBITORS
摘要
The present invention relates to a method for enhancing the physiological and therapeutic effects of an AMPA receptor potentiator in an animal by co-administration of an acetylcholinesterase inhibitor with the potentiator. Also disclosed is a method for treating a cognitive disorder in an animal by co-administration of an AMPA receptor potentiator and an acetylcholinesterase inhibitor. In addition, a composition comprising an effective amount of an AMPA receptor potentiator and an effective amount of an acetylcholinesterase inhibitor is also disclosed.
申请公布号
WO2005072345(A3)
申请公布日期
2005.12.22
申请号
WO2005US02372
申请日期
2005.01.26
申请人
CORTEX PHARMACEUTICALS INC.;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;STAUBLI, URSULA;LYNCH, GARY;ZHONG, SHENG;COLGIN, LAURA
发明人
STAUBLI, URSULA;LYNCH, GARY;ZHONG, SHENG;COLGIN, LAURA