ANTI-FCRN ANTIBODIES FOR TREATMENT OF AUTO/ALLO IMMUNE CONDITIONS

摘要

Antibodies to FcRn are provided which are non-competitive inhibitors of IgG binding to FcRn. The antibodies may be polyclonal or monoclonal or antigen binding fragment thereof. These antibodies are useful for reducing the concentration of pathogenic IgGs in individuals and therefore used as a therapeutic tool in autoimmune and alloinimune conditions.