An improved manufacturing process for methylphenidate and intermediates thereof

摘要

The present invention discloses selective and complete reduction of pyridine ring in a biaryl system comprising alpha -substituted or non-substituted benzene ringand relates more specifically, not exclusively, for the manufacture of methylphenidate, which is used for treatment of Attention Deficit Hyperactive Disorder (ADHD) and also acts as central nervous system stimulant, by using palladium/C in a solvent such as C1-C4 alcohols in presence of molar quantities of organic and/or inorganic acids.