发明名称 |
STABILIZED AQUEOUS SUSPENSIONS FOR PARENTERAL USE |
摘要 |
<p>A parenterally deliverable composition is provided, comprising an aqueous medium having dispersed therein, in solid particulate form, a steroidal drug in a therapeutically effective amount. The aqueous medium comprises one or more wetting and/or suspending agents in an amount effective to provide controlled flocculation of the drug, at least one of the wetting and/or suspending agents being susceptible to oxidative degradation. The composition further comprises, as a component thereof or as an adjunct thereto, means for protecting the oxidative degradation susceptible agent from oxidative degradation.</p> |
申请公布号 |
EP1282402(B1) |
申请公布日期 |
2005.12.21 |
申请号 |
EP20010945040 |
申请日期 |
2001.04.25 |
申请人 |
PHARMACIA ITALIA S.P.A.;PHARMACIA & UPJOHN COMPANY LLC |
发明人 |
COLOMBO, GIUSEPPE;MARTINI, ALESSANDRO;FOX, LLOYD, E. |
分类号 |
A61K47/20;A61K9/10;A61K31/56;A61K31/565;A61K31/57;A61K47/18;A61K47/24;A61P43/00;(IPC1-7):A61K9/10 |
主分类号 |
A61K47/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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