| 发明名称 |
Methods and compositions for inhibition of angiogenesis with EM-138 |
| 摘要 |
The present invention comprises a group of compounds that effectively inhibit angiogenesis. More specifically, thalidomide and various related compounds such as thalidomide precursors, analogs, metabolites and hydrolysis products have been shown to inhibit angiogenesis and to treat disease states resulting from angiogenesis. Importantly, these compounds can be administered orally.
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| 申请公布号 |
US6977268(B2) |
申请公布日期 |
2005.12.20 |
| 申请号 |
US20010026037 |
申请日期 |
2001.12.19 |
| 申请人 |
CHILDREN'S MEDICAL CENTER CORPORATION |
发明人 |
D'AMATO ROBERT |
| 分类号 |
C07D401/04;A61K9/02;A61K9/06;A61K9/08;A61K9/10;A61K9/12;A61K9/14;A61K9/20;A61K31/19;A61K31/195;A61K31/198;A61K31/40;A61K31/4015;A61K31/403;A61K31/4035;A61K31/404;A61K31/407;A61K31/44;A61K31/4427;A61K31/443;A61K31/445;A61K31/454;A61K31/535;A61K31/5377;A61K38/00;A61P1/00;A61P3/10;A61P7/04;A61P7/06;A61P9/00;A61P9/08;A61P9/10;A61P17/00;A61P17/02;A61P17/06;A61P19/00;A61P19/02;A61P19/08;A61P27/00;A61P27/02;A61P27/06;A61P27/10;A61P27/14;A61P29/00;A61P31/00;A61P31/04;A61P31/10;A61P31/12;A61P31/22;A61P33/02;A61P35/00;A61P35/02;A61P35/04;A61P37/02;A61P37/04;A61P43/00;C07C235/84;C07D207/44;C07D207/444;C07D209/46;C07D209/48;C07D403/04;C07D405/04;C07D417/04;C07D491/044;C07D491/107;(IPC1-7):A61K31/40 |
主分类号 |
C07D401/04 |
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