发明名称 |
SERTRALINE SALTS AND SUSTAINED-RELEASE DOSAGE FORMS OF SERTRALINE |
摘要 |
Sustained release dosage forms of sertraline which release sertraline at a rate between 1 mgA/hr and 40 mgA/hr. The dosage forms may exhibit an initial delay period during which sertraline is released at a rate less than 1 mgA/hr. The present invention is further directed to an acetate salt, an L-lactate salt and an L-aspartate salt of sertraline, pharmaceutical compositions thereof and methods of using that salt for treating various conditions and disorders. The present invention is also directed to processes for preparing sertraline acetate, sertraline L-lactate and sertraline L-aspartate.
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申请公布号 |
CA2290966(C) |
申请公布日期 |
2005.12.20 |
申请号 |
CA19982290966 |
申请日期 |
1998.06.15 |
申请人 |
PFIZER LIMITED |
发明人 |
HERBIG, SCOTT MAX;WEST, JAMES BLAIR;FRIESEN, DWAYNE THOMAS;AM ENDE, MARY TANYA;SHANKER, RAVI MYSORE;FRIEDMAN, HYLAR LEWIS;CURATOLO, WILLIAM JOHN |
分类号 |
A61K9/22;A61K;A61K9/00;A61K9/16;A61K9/20;A61K9/26;A61K9/28;A61K9/32;A61K9/50;A61K9/52;A61K9/54;A61K31/135;A61P3/04;A61P25/18;A61P25/24;A61P25/30;C07C209/00;C07C211/42;C07D;(IPC1-7):C07C211/42;A61P25/00;A61P37/00 |
主分类号 |
A61K9/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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