发明名称 |
Method of screening therapeutic or preventative agents for squamous epithelial cell carcinoma |
摘要 |
There is provided a method of testing squamous epithelial cells and a method of screening therapeutic agents for squamous cell carcinoma. That the base guanine at position 2128 (exon 17) of the FGFR3 gene is mutated to thymine in the cells of squamous cell carcinoma, or that the cells of squamous cell carcinoma produce an FGFR3 protein in which the amino acid glycine at position 697 is mutated to cysteine is utilized to facilitate the diagnosis and treatment of squamous cell carcinoma.
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申请公布号 |
US6977147(B2) |
申请公布日期 |
2005.12.20 |
申请号 |
US20010953562 |
申请日期 |
2001.09.17 |
申请人 |
ZERIA PHARMACEUTICAL CO., LTD. |
发明人 |
OKAMOTO TETSUJI |
分类号 |
G01N33/50;A61K45/00;A61P35/00;C12N15/09;C12Q1/68;G01N33/15;G01N33/574;(IPC1-7):C12Q1/68;C12P19/34;C07H21/04;C12N5/10 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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