发明名称 |
ANGIOGENESIS PROMOTION BY PROSTAGLANDIN COMPOSITIONS AND METHODS |
摘要 |
The present invention provides compositions and methods for promoting the recovery of vascular function in erectile dysfunction associated with vasculopathy by administering a composition comprising a vasoactive prostaglandin and a biocompatible polymer. In preferred embodiments, the prostaglandin composition is a topical composition comprising prostaglandin E1, a biocompatible polymer and a penetration enhancer and the topical composition is applied to the meatus at the tip of the penis. In another embodiment, the invention provides a method for increasing microvascular outgrowth at a targeted arterial segment comprising administering a prostaglandin E1 composition to produce an extracellular prostaglandin E1concentration of about 1 micromolar to about 10 micromolar adjacent to the targeted arterial segment for about four days.
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申请公布号 |
KR20050119136(A) |
申请公布日期 |
2005.12.20 |
申请号 |
KR20057017710 |
申请日期 |
2005.09.21 |
申请人 |
NEXMED HOLDINGS, INC. |
发明人 |
LIN GUITING;MO JOSEPH Y.;LU MINGQI;GUO YINGLU |
分类号 |
A61K9/00;A61K31/557;A61K31/5575;A61K47/02;A61K47/10;A61K47/14;A61K47/18;A61K47/26;A61K47/36;(IPC1-7):A61K31/557 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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