发明名称 |
Compositions and treatments for inhibiting kinase and/or HMG-CoA reductase |
摘要 |
The present invention provides compositions of matter, kits and methods for their use in the treatment of MAP kinase-related conditions and/or HMG-CoA reductase-related conditions. In particular, the invention provides compositions for treating inflammatory and/or cardiovascular conditions in an animal subject by inhibiting p38alpha MAP kinase and/or HMG-CoA reductase, as well as providing formulations and modes of administering such compositions. The invention further provides methods for the rational design of inhibitors of MAP kinase, HMG-CoA reductase, or both for use in the practice of the present invention.
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申请公布号 |
US2005277653(A1) |
申请公布日期 |
2005.12.15 |
申请号 |
US20050118065 |
申请日期 |
2005.04.29 |
申请人 |
GRIFFIN JOHN;LANZA GUIDO;YU JESSEN |
发明人 |
GRIFFIN JOHN;LANZA GUIDO;YU JESSEN |
分类号 |
A61K31/4172;A61K31/4178;A61K31/4439;A61K31/506;C07D233/60;C07D401/04;C07D403/04;C07D405/14;(IPC1-7):A61K31/506;A61K31/443;A61K31/417;C07D45/02 |
主分类号 |
A61K31/4172 |
代理机构 |
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地址 |
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