摘要 |
A compound represented by the following formula, a salt thereof or a hydrate of the foregoing has an excellent hepatocyte growth factor receptor (HGFR) inhibitory activity, and exhibits anti-tumor activity, angiogenesis inhibitory activity and cancer metastasis inhibitory activity. [R<SUP>1 </SUP>represents C<SUB>1-6 </SUB>alkyl or the like; R<SUP>2 </SUP>and R<SUP>3 </SUP>represent hydrogen; R<SUP>4</SUP>, R<SUP>5</SUP>, R<SUP>6</SUP>, and R<SUP>7 </SUP>may be the same or different and each represents hydrogen, halogen, C<SUB>1-6 </SUB>alkyl or the like; R<SUP>8 </SUP>represents hydrogen or the like; R<SUP>9 </SUP>represents C<SUB>1-6 </SUB>alkyl or the like; V<SUP>1 </SUP>represents oxygen or the like; V<SUP>2 </SUP>represents oxygen or sulfur; W represents -NH- or the like; X represents -CH-, nitrogen or the like; and Y represents oxygen or the like.]
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