<p>The present invention provides the identification of genes that are expressed in tumors that are responsive to a given therapeutic agent and whose expression (either increased expression or decreased expression) correlates with responsiveness to that therapeutic agent. One or more of the genes of the present invention can be used as markers (or surrogate markers) to identify tumors that are likely to be successfully treated by that agent.</p>
申请公布号
CA2569202(A1)
申请公布日期
2005.12.15
申请号
CA20042569202
申请日期
2004.09.30
申请人
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM;MILLENIUM PHARMACEUTICALS, INC.
发明人
PUSZTAI, LAJOS;SYMMANS, FRASER W.;AYERS, MARK;HESS, KENNETH R.;STEC, JAMES