METHOD FOR SCREENING AND COMPOSITIONS FOR TREATING CANCERS

摘要

The invention relates to compositions and methods for treating proliferative pathologies, in particular cancers. Said invention is based on identifying TReP-132 particular properties for controlling a cellular cycle of cellular proliferation. Said protein exhibits a tumor-suppressing activity, thereby being a preferred target for developing efficient therapeutic strategies. The compositions, the use and methods for identifying compounds which are capable to modulate the activity of said protein and which are usable for treating different proliferative pathologies, in particular of a human being are also disclosed.