| 发明名称 |
COMPOUNDS, COMPOSITIONS AND METHODS FOR STABILIZING TRANSTHYRETIN AND INHIBITING TRANSTHYRETIN MISFOLDING |
| 摘要 |
Compounds, compositions and methods are provided for stabilizing transthyretin and for treating, preventing, or ameliorating one or more symptoms of transthyretin mediated diseases. In one embodiment, the compounds are biphenyls and related compounds. |
| 申请公布号 |
WO2005118511(A2) |
申请公布日期 |
2005.12.15 |
| 申请号 |
WO2005US19184 |
申请日期 |
2005.05.20 |
| 申请人 |
THE SCRIPPS RESEARCH INSTITUTE;KELLY, JEFFREY, W. |
发明人 |
KELLY, JEFFREY, W. |
| 分类号 |
A61K31/19;A61K31/192;A61K31/195;A61K31/343;A61K31/41;A61K31/4184;A61K31/423;A61K31/428;A61K31/69;C07D263/57;C07D307/91;C07D413/04;C07F5/02 |
主分类号 |
A61K31/19 |
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