发明名称 |
METHODS AND COMPOSITIONS FOR THE TREATMENT OF POLYCYSTIC DISEASES |
摘要 |
<p>This invention provides compositions and methods to diagnose and treat polycystic disorders by inhibiting the biological activity of a gene now correlated with appearance of this disorder. By way of illustrative only, th e Connective Tissue Growth Factor (CTGF) gene is an example of such a gene. Al so provided by this invention are compositions and methods to treat or ameliora te abnormal cystic lesions and diseases associated with the formation of cysts in tissue. The methods and compositions treat and ameliorate pathological cyst formation in tissue by inhibiting or augmenting gene expression or the biological activity of its gene expression product or its receptor.</p> |
申请公布号 |
CA2564092(A1) |
申请公布日期 |
2005.12.15 |
申请号 |
CA20052564092 |
申请日期 |
2005.04.29 |
申请人 |
GENZYME CORPORATION |
发明人 |
BESKROVNAYA, OXANA;HUSSON, HERVE |
分类号 |
A61K48/00;A61K38/17;A61K39/395;C07K16/22 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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