发明名称 Pharmaceutical compositions comprising cyclosporins
摘要 A liquid comprising a therapeutically effective concentration of a cyclosporin and a vitamin E tocopherol polyethylene glycol succinate, wherein said liquid is an aqueous solution, and wherein no hydrophilic organic solvent is present at a concentration greater than half of that of the cyclosporin is also disclosed herein. A composition comprising a therapeutically effective concentration of cyclosporin A and an effective amount of a vitamin E tocopherol polyethylene glycol succinate, wherein said composition is an aqueous liquid solution which is intended for ophthalmic use, and wherein no hydrophilic organic solvent is present at a mass concentration greater than or equal to that of the cyclosporin, is disclosed herein. A composition comprising a therapeutically effective concentration of cyclosporin A and an effective amount of a vitamin E tocopherol polyethylene glycol succinate, wherein said composition is an aqueous liquid solution which is intended for parenteral use, and wherein no hydrophilic organic solvent is present at a mass concentration greater than or equal to that of the cyclosporin, is disclosed herein. Methods of treating diseases or conditions using said compositions, and medicaments related thereto, are also disclosed herein.
申请公布号 US2005277584(A1) 申请公布日期 2005.12.15
申请号 US20040865638 申请日期 2004.06.09
申请人 ALLERGAN, INC. 发明人 TIEN WALTER L.;GRAHAM RICHARD;CHANG JAMES N.
分类号 A61K9/00;A61K9/08;A61K31/355;A61K38/13;A61K47/22;(IPC1-7):A61K38/13 主分类号 A61K9/00
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