BIOSYNTHETIC GENE CLUSTER FOR TAUTOMYCETIN

摘要

Domains of tautomycetin polyketide synthase and modification enzymes and polynucleotides encoding them are provided. Methods to prepare tautomycetin in pharmaceutically useful quantities are described, as are methods to prepare tautomycetin analogs and other polyketides using the polynucleotides encoding tautomycetin synthase domains or modifying enzymes.