发明名称 |
COMBINATION THERAPY WITH GLATIRAMER ACETATE AND ALPHACALCIDOL FOR THE TREATMENT OF MULTIPLE SCLEROSIS |
摘要 |
The subject invention provides a method of treating a subject afflicted with a form of multiple sclerosis comprising periodically administering to the subject an amount of glatiramer acetate and an amount of alphacalcidol, wherein the amounts when taken together are effective to alleviate a symptom of the form of multiple sclerosis in the subject so as to thereby treat the subject. The subject invention also provides a package comprising glatiramer acetate, alphacalcidol and instructions for use of them together to alleviate a symptom of a form of multiple sclerosis in a subject. Additionally, the subject invention provides a pharmaceutical composition comprising an amount of glatiramer acetate and an amount of alphacalcidol, wherein the amounts when taken together are effective to alleviate a symptom of a form of multiple sclerosis in a subject. The subject invention further provides a pharmaceutical combination comprising separate dosage forms of an amount of glatiramer acetate and an amount of alphacalcidol, which combination is useful to alleviate a symptom of a form of multiple sclerosis in a subject. |
申请公布号 |
EP1603530(A1) |
申请公布日期 |
2005.12.14 |
申请号 |
EP20040717461 |
申请日期 |
2004.03.04 |
申请人 |
TEVA PHARMACEUTICAL INDUSTRIES LIMITED |
发明人 |
PINCHASI, ISRIT;KOFLER, DINA;HAYARDENY, LIAT |
分类号 |
A61K38/12;A61K38/16;A61K45/06;(IPC1-7):A61K9/00;A61K31/05;A61K31/045 |
主分类号 |
A61K38/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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