发明名称 COMBINATION THERAPY WITH GLATIRAMER ACETATE AND ALPHACALCIDOL FOR THE TREATMENT OF MULTIPLE SCLEROSIS
摘要 The subject invention provides a method of treating a subject afflicted with a form of multiple sclerosis comprising periodically administering to the subject an amount of glatiramer acetate and an amount of alphacalcidol, wherein the amounts when taken together are effective to alleviate a symptom of the form of multiple sclerosis in the subject so as to thereby treat the subject. The subject invention also provides a package comprising glatiramer acetate, alphacalcidol and instructions for use of them together to alleviate a symptom of a form of multiple sclerosis in a subject. Additionally, the subject invention provides a pharmaceutical composition comprising an amount of glatiramer acetate and an amount of alphacalcidol, wherein the amounts when taken together are effective to alleviate a symptom of a form of multiple sclerosis in a subject. The subject invention further provides a pharmaceutical combination comprising separate dosage forms of an amount of glatiramer acetate and an amount of alphacalcidol, which combination is useful to alleviate a symptom of a form of multiple sclerosis in a subject.
申请公布号 EP1603530(A1) 申请公布日期 2005.12.14
申请号 EP20040717461 申请日期 2004.03.04
申请人 TEVA PHARMACEUTICAL INDUSTRIES LIMITED 发明人 PINCHASI, ISRIT;KOFLER, DINA;HAYARDENY, LIAT
分类号 A61K38/12;A61K38/16;A61K45/06;(IPC1-7):A61K9/00;A61K31/05;A61K31/045 主分类号 A61K38/12
代理机构 代理人
主权项
地址