A method and device to obtain haematological parameters and indicators by means of harnessing the dynamics of erythrocyte and other aggregation

摘要

A method and device to harness the dynamic properties of aggregating erythrocytes and other blood aggregations in vitro or in vivo to indicate a haematological parameter comprises, mixing a blood sample to a predefined rate of shear or for a predetermined mixing time if in vitro, or halting or reducing blood flow for a predetermined duration if in vivo, selecting a defined region in the temporal evolution of the aggregation, making at least two time successive remote examinations to yield quantities which reflect the aggregation state, and mathematically manipulating said quantities together to correlate with or indicate the haematological parameter. A capacitance measuring system measures dielectric properties of the blood samples by applying a frequency (A1) to a sample cell.