METHOD FOR THE IDENTIFICATION OF A POLYPEPTIDE WHICH BINDS TO A GIVEN PMHC COMPLEX
摘要
<p>A method for the identification of a polypeptide which binds to a given peptide-MHC complex or CD1-antigen complex, and to a nucleoprotein display library wherein the nucleoprotein particles display polypeptides comprising diverse synthetic T cell receptor variable domain sequences derived from one or more TCRs which bind a first peptide MHC complex or CD1-antigen.</p>