发明名称 COMPOSITIONS FOR IMPROVING BREAST HEALTH IN WOMAN
摘要 Disclosed are compositions and corresponding methods for treating fibrocysti c breast disease or other breast-related disease or condition. The composition s comprise, per serving or dose, from zero to about 400 ~g selenium, from abou t 100 mg to about 6000 mg gamma linolenic acid, and about 0.15mg to about 5 mg iodine, with nutritional embodiments further comprising one or more of protein, fat, carbohydrate, vitamins, and minerals and providing from about 50 to about 1000 kcal of energy per severing or dose. Also disclosed are in-vit ro studies showing that certain combinations of gamma linolenic acid, iodine, and/or selenium may 1) inhibit breast cancer or fibrocystic cell proliferation, 2) reinforce the function of tight junctions of endothelial cells and of mammary epithelial cells in estrogen-sensitive conditions, and 3) reduce the risk of vascular invasion by breast cancer cells.
申请公布号 CA2564592(A1) 申请公布日期 2005.12.08
申请号 CA20052564592 申请日期 2005.04.28
申请人 ABBOTT LABORATORIES 发明人 MAZER, TERRY B.;DEWILLE, NORMANELLA T.;SETH, ANAND;DAS, TAPAS;SHALWITZ, ROBERT A.;RUSHLOW, KEITH E.
分类号 A61K31/202;A23L1/29;A23L1/30;A23L1/304;A61K33/04;A61K33/18;A61K45/06;A61P39/00 主分类号 A61K31/202
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