MICROPELLET CONTAINING PELLETS AND METHOD OF PREPARING SUCH PELLETS

摘要

The invention provides novel pellets adapted for biologically active
preparations and a novel process for preparing said pellets. The novel pellets
are adapted for use in the delivery of a biologically active agent. The
pellets have an inner zone comprising a plurality of micropellets which are
bound together to form a pellet when the micropellets are dispersed in a
matrix of an inert pharmaceutical excipient, a biologically active agent and
optionally having an outer zone comprising a surface layer comprising a
pharmaceutical excipient with or without a biologically active agent. The
pellets will have an arcuate surface due to the manner in which they are
formed.