ADENYLYL CYCLASE ANTIBODIES, COMPOSITIONS AND USES THEREOF
摘要
The invention relates to compositions and methods for diagnosing and treating cardiac conditions and neurodegenerative diseases using antibodies which specifically recognize and bind to the adenylyl cyclase 5 isoform in the heart and brain. These antibodies demonstrate high specificity to the AC5 isoform and do not cross react to any other AC5 isoform. The invention further relates to methods of delivery of drugs to the site of injured tissue using the antibodies of the present invention.
申请公布号
WO2005115121(A2)
申请公布日期
2005.12.08
申请号
WO2005US18589
申请日期
2005.05.26
申请人
UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY;VATNER, STEPHEN, F.;VATNER, DOROTHY, E.;SADOSHIMA, JUNICHI;PAIN, JAYASHREE