摘要 |
The present invention is to provide a bicyclic compound represented by the following formula: wherein Ring Q is pyridine or pyrimidine; Ring A is benzene or a heterocyclic ring; G is Ring B optionally having a substituent(s) R<3>, or an amino optionally substituted by one or two selected from the group consisting of alkyl(s), aralkyl(s) and cycloalkyl(s); Ring B is benzene, a heterocyclic ring, a cycloalkane or a cycloalkene; R<1> is a group selected from the following formulae: R<2> and R<3> may be the same or different from each other, and each is cyano, nitro, etc.; m is 0, 1 or 2; R<4> is hydrogen, a halogen, etc.; and R<5> and R<6> may be the same or different from each other, and each is hydrogen, an optionally substituted alkyl, etc., or a pharmaceutically acceptable salt thereof, which is a large conductance calcium-activated K channel opener useful for treatment of pollakiuria, urinary incontinence, etc. |
申请人 |
TANABE SEIYAKU CO., LTD.;HIRAI, MIKI;KUSAMA, MARI;HOSAKA, TOSHIHIRO;KOHNOMI, SHUNTAROU |
发明人 |
HIRAI, MIKI;KUSAMA, MARI;HOSAKA, TOSHIHIRO;KOHNOMI, SHUNTAROU |