TOCOPHEROL DERIVATIVE, ASCORBIC ACID DERIVATIVE AND SKIN PREPARATION FOR EXTERNAL USE COMPRISING SURFACTANT HAVING LIPOPEPTIDE STRUCTURE

摘要

PROBLEM TO BE SOLVED: To provide a skin preparation for external use (including cosmetics) which simultaneously comprises at least a tocopherol glycine ester and an ascorbic acid compound and is enhanced in stability with time. SOLUTION: The skin preparation for external use comprises (A) a tocopherol glycine ester, (B) an ascorbic acid-2-phosphoric acid ester and a specific amount of (C) an anionic surfactant having a lipopeptide structure. The skin preparation for external use (including cosmetics) exhibits enhanced stability of the tocopherol glycine ester and is prevented from discoloration (including turbidity) of the preparation and/or generation of precipitation with the lapse of time though it simultaneously contains the tocopherol glycine ester and the ascorbic acid compound to effectively exhibit efficacy and effects thereof over a long period of time. COPYRIGHT: (C)2006,JPO&NCIPI