M-CSF muteins are provided, along with pharmaceutical compositions containing a M-CSF mutein, kits containing a pharmaceutical composition, methods of preventing and treating bone metastases in a subject afflicted with metastatic cancer, and methods of screening for M-CSF muteins.
申请公布号
WO2005070447(A3)
申请公布日期
2005.12.08
申请号
WO2005US01630
申请日期
2005.01.21
申请人
CHIRON CORPORATION;ZIMMERMAN, DEBORAH LEE;HARROWE, GREGORY MARTIN;LIU, CHENG;KOTHS, KIRSTON;KAVANAUGH, WILLIAM MICHAEL;LONG, LI
发明人
ZIMMERMAN, DEBORAH LEE;HARROWE, GREGORY MARTIN;LIU, CHENG;KOTHS, KIRSTON;KAVANAUGH, WILLIAM MICHAEL;LONG, LI