发明名称 Process for production of piperidine derivatives
摘要 The present invention discloses processes for preparing piperidine derivative compounds of the formulae: wherein n is 0 or 1; R<SUP>1 </SUP>is hydrogen or hydroxy; R<SUP>2 </SUP>is hydrogen; or, when n is 0 , R<SUP>1 </SUP>and R<SUP>2 </SUP>taken together form a second bond between the carbon atoms bearing R<SUP>1 </SUP>and R<SUP>2</SUP>, provided that when n is 1 , R<SUP>1 </SUP>and R<SUP>2 </SUP>are each hydrogen; R<SUP>3 </SUP>is -COOH or -COOR<SUP>4</SUP>; R<SUP>4 </SUP>is an alkyl or aryl moiety; A, B, and D are the substituents of their rings, each of which may be different or the same, and are selected from the group consisting of hydrogen, halogens, alkyl, hydroxy, alkoxy, and other substituents.
申请公布号 US2005272771(A1) 申请公布日期 2005.12.08
申请号 US20050123275 申请日期 2005.05.06
申请人 AMR TECHNOLOGY, INC. 发明人 D'AMBRA THOMAS E.;PILLING GARRY M.
分类号 A61K31/00;A61K31/42;A61K31/421;A61K31/445;A61P37/00;A61P37/08;C07D211/22;C07D211/54;C07D261/04;C07D263/10;(IPC1-7):C07D211/54 主分类号 A61K31/00
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