发明名称 |
N-SUBSTITUIETE HETEROARYLOXY-ARYL-SPIRO-PYRIMIDINE-2,4,6-TRION METALLOPROTEINASE INHIBITOREN |
摘要 |
The present invention relates to N-substituted-heteroaryloxy-aryl-spiro-pyrimidine-2,4,6-trione metalloproteinase inhibitors of the formula wherein ring X is a 5-7 membered heterocyclic ring, and wherein A, Y, B, and G are as defined in the specification; and to pharmaceutical compositions and methods of treating inflammation, cancer and other disorders. |
申请公布号 |
DE60302150(D1) |
申请公布日期 |
2005.12.08 |
申请号 |
DE2003602150 |
申请日期 |
2003.04.15 |
申请人 |
PFIZER PRODUCTS INC., GROTON |
发明人 |
NOE, CARL;FREEMAN-COOK, DANIEL |
分类号 |
A61K31/527;A61P1/16;A61P3/00;A61P9/00;A61P11/00;A61P13/12;A61P17/00;A61P19/02;A61P25/02;A61P27/02;A61P29/00;A61P31/00;A61P35/00;A61P37/00;A61P37/08;A61P43/00;C07D487/10;(IPC1-7):C07D487/10 |
主分类号 |
A61K31/527 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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