Materials and methods are provided to prepare therapeutic conjugates for the treatment of proliferative diseases. The therapeutic conjugates of the invention comprise a targeting moiety conjugated to a therapeutic moiety. The therapeutic moiety of the conjugates of the present invention have a cytotoxic effect and are useful in the teratment of proliferative diseases.
申请公布号
WO2005116255(A2)
申请公布日期
2005.12.08
申请号
WO2005US12797
申请日期
2005.04.15
申请人
ARCHEMIX CORPORATION;STANTON, MARTIN;KURZ, MARKUS;WILSON, CHARLES
