| 发明名称 |
THE METHOD OF IN VITRO DETECTING ABERRANT gastric DYSPLASIA |
| 摘要 |
<p>The present invention provides a method for in vitro detection of malignant potential of dysplasia by aberrant methylation of p16 CpG islands, composing extraction of genomic DNA from tissue or body fluid samples, analysis of methylation status of p16 CpG islands, evaluation of malignant potential of testing tissues. The present invention also provides a group of artificial sequences of p16 CpG island with or without methylation.</p> |
| 申请公布号 |
EP1602731(A1) |
申请公布日期 |
2005.12.07 |
| 申请号 |
EP20030711792 |
申请日期 |
2003.03.13 |
| 申请人 |
BEIJING INSTITUTE FOR CANCER RESEARCH |
发明人 |
BAI, HUA;SUN, YU;ZHOU, JING;LI, JIYU;DENG, DAJUN |
| 分类号 |
C12Q1/68;(IPC1-7):C12Q1/68 |
主分类号 |
C12Q1/68 |
| 代理机构 |
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