发明名称 |
Regulated transcription of targeted genes and other biological events |
摘要 |
Dimerization and oligomerization of proteins are general biological control mechanisms that contribute to the activation of cell membrane receptors, transcription factors, vesicle fusion proteins, and other classes of intra- and extracellular proteins. We have developed a general procedure for the regulated (inducible) dimerization or oligomerization of intracellular proteins. |
申请公布号 |
US6972193(B1) |
申请公布日期 |
2005.12.06 |
申请号 |
US19990466568 |
申请日期 |
1999.12.17 |
申请人 |
PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
CRABTREE GERALD R.;SCHREIBER STUART L.;SPENCER DAVID M.;WANDLESS THOMAS J.;HO STEFFAN N.;BELSHAW PETER |
分类号 |
A61K38/00;A61K47/48;C07D498/18;C07F5/02;C07H19/01;C07K7/64;C07K14/395;C07K14/705;C07K14/71;C07K14/725;C12N5/10;C12N15/10;C12N15/62;C12N15/63;C12P15/00;(IPC1-7):C12N5/10 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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