发明名称 |
Humanized immunoglobulin reactive with B7-2 and methods of treatment therewith |
摘要 |
The invention relates to a humanized anti-B7-2 antibody that comprises a variable region of nonhuman origin and at least a portion of an immunoglobulin of human origin. The invention also pertains to methods of treatment for various autoimmune diseases, transplant rejection, inflammatory disorders and infectious diseases by administering humanized anti-B7-2 and/or anti-B7-1 antibodies. |
申请公布号 |
US6972125(B2) |
申请公布日期 |
2005.12.06 |
申请号 |
US19990249011 |
申请日期 |
1999.02.12 |
申请人 |
GENETICS INSTITUTE, LLC |
发明人 |
CO MAN SUNG;VASQUEZ MAXIMILIANO;CARRENO BEATRIZ;CELNIKER ABBIE CHERYL;COLLINS MARY;GOLDMAN SAMUEL;GRAY GARY S.;KNIGHT ANDREA;O'HARA DENISE;RUP BONITA;VELDMAN GEERTRUIDA M. |
分类号 |
A61K39/395;C07K16/28;(IPC1-7):A61K39/395;C12N15/13 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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