| 发明名称 |
PROCESS FOR PREPARING THE ANTIVIRAL AGENT [1S- (1ALPHA, 3 ALPHA, 4 BETA)] -2-AMINO-1, 9-DIHYDRO- 9-[4-HYDROXY- 3-(HYDROXYMETHYL) -2-METHYLENECYCLO. |
| 摘要 |
<p>Processes are disclosed for preparing the antiviral agent entecavir. A resin adsorption process for the isolation and purification of entecavir is also disclosed. Various intermediates useful in the preparation of entecavir are also disclosed.</p> |
| 申请公布号 |
MXPA05005971(A) |
申请公布日期 |
2005.12.05 |
| 申请号 |
MX2005PA05971 |
申请日期 |
2003.12.10 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY. |
发明人 |
DAVID R. KRONENTHAL |
| 分类号 |
C07D473/12;C07D473/18;C07F7/08;C07F7/18;(IPC1-7):A61K00/00 |
主分类号 |
C07D473/12 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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