| 发明名称 |
HUMANIZED ANTIBODY AGAINST HUMAN TISSUE FACTOR (TF) AND PROCESS FOR PRODUCING HUMANIZED ANTIBODY |
| 摘要 |
PROBLEM TO BE SOLVED: To provide a process for producing natural humanized antibody against human tissue factor (TF). SOLUTION: The antibody is produced by production method of a natural humanized antibody having complementarity determining region (CDR) derived from nonhuman and framework region (FR) derived from a natural human antibody, and deceased in immunogenicity. COPYRIGHT: (C)2006,JPO&NCIPI
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| 申请公布号 |
JP2005330292(A) |
申请公布日期 |
2005.12.02 |
| 申请号 |
JP20050187422 |
申请日期 |
2005.06.27 |
| 申请人 |
CHUGAI PHARMACEUT CO LTD |
发明人 |
SATO ISAO;ADACHI HIDEKI;YABUTA HISAHIRO |
| 分类号 |
C12N15/09;A61K39/395;A61P1/16;A61P7/02;A61P17/02;A61P31/00;A61P35/00;C07K16/28;C12P21/08;(IPC1-7):C07K16/28 |
主分类号 |
C12N15/09 |
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