摘要 |
<p><P>PROBLEM TO BE SOLVED: To obtain a low molecule medicine composition which aims at platelet production recovery for thrombocytopenia-accompanying diseases, and the like. <P>SOLUTION: A specific megakaryocyte production-inducing agent has activities for proliferating and differentiating hematopoietic stem cells or megakaryocyte precursor cells. Especially, the agent is either one of 4-(5-octylpyrimidin-2-yl)phenol, 4-[2-(4-butoxyphenyl)pyrimidin-5-yl]phenol, 2-(octylphenyl)pyrimidin-5-ol, 4-(5-octylpyridin-2-yl)phenol, 4-(6-pentylquinolin-2-yl)phenol, and 4-ä2-[4-(dithyroxy)-2,3-difluorophenyl]pyrimidin-5-yl}phenol. <P>COPYRIGHT: (C)2006,JPO&NCIPI</p> |