发明名称 MEGAKARYOCYTE PRODUCTION-INDUCING AGENT
摘要 <p><P>PROBLEM TO BE SOLVED: To obtain a low molecule medicine composition which aims at platelet production recovery for thrombocytopenia-accompanying diseases, and the like. <P>SOLUTION: A specific megakaryocyte production-inducing agent has activities for proliferating and differentiating hematopoietic stem cells or megakaryocyte precursor cells. Especially, the agent is either one of 4-(5-octylpyrimidin-2-yl)phenol, 4-[2-(4-butoxyphenyl)pyrimidin-5-yl]phenol, 2-(octylphenyl)pyrimidin-5-ol, 4-(5-octylpyridin-2-yl)phenol, 4-(6-pentylquinolin-2-yl)phenol, and 4-ä2-[4-(dithyroxy)-2,3-difluorophenyl]pyrimidin-5-yl}phenol. <P>COPYRIGHT: (C)2006,JPO&NCIPI</p>
申请公布号 JP2005330204(A) 申请公布日期 2005.12.02
申请号 JP20040148779 申请日期 2004.05.19
申请人 OTSUKA PHARMACEUT CO LTD 发明人 KASHIWAKURA IKURO;YOSHIZAWA ATSUSHI
分类号 C07D239/26;A61K31/4418;A61K31/47;A61K31/505;A61P7/02;A61P7/04;A61P7/06;A61P31/04;A61P35/00;A61P35/02;A61P37/02;C07D213/30;C07D215/14;(IPC1-7):A61K31/441 主分类号 C07D239/26
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