发明名称 |
Bicyclic heterocycles as HIV integrase inhibitors |
摘要 |
The invention encompasses a series cyclic bicyclic pyrimidinone compounds of Formula I which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.
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申请公布号 |
US2005267105(A1) |
申请公布日期 |
2005.12.01 |
申请号 |
US20050126891 |
申请日期 |
2005.05.11 |
申请人 |
NAIDU B N;BANVILLE JACQUES;BEAULIEU FRANCIS;CONNOLLY TIMOTHY P;KRYSTAL MARK R;MATISKELLA JOHN D;OUELLET CARL;PLAMONDON SERGE;REMILLARD ROGER;SORENSON MARGARET E;UEDA YASUTSUGU;WALKER MICHAEL A |
发明人 |
NAIDU B. N.;BANVILLE JACQUES;BEAULIEU FRANCIS;CONNOLLY TIMOTHY P.;KRYSTAL MARK R.;MATISKELLA JOHN D.;OUELLET CARL;PLAMONDON SERGE;REMILLARD ROGER;SORENSON MARGARET E.;UEDA YASUTSUGU;WALKER MICHAEL A. |
分类号 |
A61K31/519;A61K31/538;A61P31/18;C07D491/04;C07D498/04;(IPC1-7):A61K31/538 |
主分类号 |
A61K31/519 |
代理机构 |
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代理人 |
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地址 |
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