| 发明名称 |
Peptides of CaV2.2 that inhibit pain |
| 摘要 |
The present invention relates to peptides of CaV2.2 and their use in the treatment of pain. The sequence of the peptides is derived from the C-terminus of CaV2.2. and is believed to inhibit the interaction of CaV2.2 with Mint1-PDZ1. The invention is related to use of this peptide to treat pain and to use of this peptide in binding reaction with int-PDZ to screen for small molecules that can inhibit pain.
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| 申请公布号 |
US2005267036(A1) |
申请公布日期 |
2005.12.01 |
| 申请号 |
US20050096281 |
申请日期 |
2005.03.31 |
| 申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
GARRY MARY;BEZPROZVANNY ILYA |
| 分类号 |
A61K38/00;A61K38/06;A61K38/08;A61K38/10;A61K38/17;C07K5/113;C07K7/06;C07K7/08;C07K14/47;C07K14/705;C12N15/12;G01N33/68;(IPC1-7):A61K38/10 |
主分类号 |
A61K38/00 |
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