| 发明名称 |
Glyceraldehyde 3-phosphate dehydrogenase-S (GAPDHS), a glycolytic anzyme expressed only in male germ cells, is a target for male contraception |
| 摘要 |
Methods for identifying modulators of a male germ cell-specific glyceraldehyde 3-phosphate dehydrogenase (GAPDHS) are disclosed. Also disclosed are methods for screening potential modulators for an ability to modulate biological functions of a GAPDHS polypeptide.
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| 申请公布号 |
US2005266515(A1) |
申请公布日期 |
2005.12.01 |
| 申请号 |
US20050140417 |
申请日期 |
2005.05.27 |
| 申请人 |
THE GOV. OF THE U.S.A AS REPRESENTED BY THE SECRETARY OF THE DEPT. OF HEALTH & HUMAN SERVICES |
发明人 |
O'BRIEN DEBORAH A.;EDDY EDWARD M. |
| 分类号 |
A61K31/56;A61K38/54;C12N9/02;C12P21/04;C12Q1/26;C12Q1/32;G01N33/48;G01N33/50;G01N33/573;G06F19/16;G06F19/18;(IPC1-7):A61K38/54;G06F19/00 |
主分类号 |
A61K31/56 |
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