| 摘要 |
Apparatus, computer system, computer program and storage medium for determining intrathoracic blood volume (ITBV) and other cardio-vascular parameters of a patient by thermodilution measurements. The apparatus comprises a) temperature influencing means ( 107 ) for provoking an initial local temperature change in the proximity of a first place ( 101 ) of a patient's vascular system ( 103 ), thus introducing a travelling temperature deviation to patient's blood stream, b) a temperature sensor device ( 117 ) for measuring the local temperature of patient's blood at a second place ( 102 ) of patient's vascular system ( 103 ) downstream of said first place ( 101 ) c) a computer system ( 104 ) coupled to said temperature sensor device ( 117 ) and adapted to record said patient's local blood temperature measured at said second place ( 102 ) as a function of time to determine a thermodilution curve, d) said computer system ( 104 ) being further adapted to determine patient's global enddiastolic blood volume (GEDV) and patient's intrathoracic thermovolume (ITTV) from said thermodilution curve, e) said computer system ( 104 ) being further adapted to determine patient's intrathoracic blood volume (ITBV) according to the following formula: <?in-line-formulae description="In-line Formulae" end="lead"?>ITBV=f(GEDV, ITTV, P), <?in-line-formulae description="In-line Formulae" end="tail"?> ITBV being the intrathoracic blood volume, GEDV being the global enddiastolic blood volume, ITTV being the intrathoracic thermovolume, P being an airway pressure inside patient's lungs. By determining ITBV not only from GEDV but also as a function of ITTV and P enhanced accuracy can be obtained, especially if the patient suffers from pulmonary edema and/or is mechanically ventilated.
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