发明名称 Watersoluble prodrugs of propofol
摘要 The present invention relates to propofol derivatives comprising a cyclic or linear amino acid, or a poly- or (oligo)saccharide moiety, a process for preparing said derivatives, a method for anesthetizing a mammal as well as a method for treating convulsions, migraine or related diseases, or for the inhibition of free radicals in a mammal to which said compounds are administered. Furthermore, the present invention relates to said compounds for use as a medicament and the use of said compounds for the preparation of a medicament for anesthetizing a mammal or for treating convulsions, migraine or related diseases, or for inhibition of free radicals in a mammal.
申请公布号 US2005267169(A1) 申请公布日期 2005.12.01
申请号 US20050100746 申请日期 2005.04.07
申请人 ORLANDO MICHELE;HEMBERGER JURGEN;TRAPANI GIUSEPPE;LISO GAETANO;ALTOMARE COSIMO;LATROFA ANDREA;BIGGIO GIOVANNI;SERRA MARIANGELA;SANNA ENRICO;LAQUINTANA VALENTINO 发明人 ORLANDO MICHELE;HEMBERGER JURGEN;TRAPANI GIUSEPPE;LISO GAETANO;ALTOMARE COSIMO;LATROFA ANDREA;BIGGIO GIOVANNI;SERRA MARIANGELA;SANNA ENRICO;LAQUINTANA VALENTINO
分类号 A61K47/48;C07C229/08;C07C229/22;C07C229/24;C07C237/06;C07C323/58;C07D207/16;C07D211/60;C07D211/62;C07H15/203;(IPC1-7):A61K31/455;A61K31/401 主分类号 A61K47/48
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