发明名称 |
CHIMERIC SOLUBLE HYPER IL-11 AND USE THEREOF |
摘要 |
<p>The present invention concerns a new designer cytokine termed H11, which is constructed by fusion of two soluble components, soluble interleukin 11 receptor (sIL-11 R) and interleukin 11 (IL-11) using their natural sequence and its use for the production of a medicament for treating or preventing a disease selected from the group consisting of a proliferative disease, a cytopathy, radiation damage, an IL-11 dependent inflammatory disorder, IL-11 dependent degenerative disorder and IL-11 dependent or mediated soft tissue disorder.</p> |
申请公布号 |
WO2005113591(A1) |
申请公布日期 |
2005.12.01 |
申请号 |
WO2005EP05494 |
申请日期 |
2005.05.20 |
申请人 |
AGIRX LIMITED;MACKIEWICZ, ANDRZEJ;DAMS-KOZLOWSKA, HANNA;ROSE-JOHN, STEFAN |
发明人 |
MACKIEWICZ, ANDRZEJ;DAMS-KOZLOWSKA, HANNA;ROSE-JOHN, STEFAN |
分类号 |
A61K38/00;A61K38/20;C07K14/54;C07K14/715;C12N15/62;(IPC1-7):C07K14/54 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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