TNF SUPER FAMILY MEMBERS WITH ALTERED IMMUNOGENICITY
摘要
The present invention relates to non-naturally occurring variant Tumor Necrosis Factor Super Family member proteins with reduced immunogenicity. More specifically, the present invention relates to variant BAFF, RANKL, TRAIL, CD40L and APRIL proteins with reduced immunogenicity.
申请公布号
WO2005113598(A2)
申请公布日期
2005.12.01
申请号
WO2005US18130
申请日期
2005.05.23
申请人
XENCOR, INC.;MARSHALL, SHANNON, ALICIA;MOORE, GREGORY, L.;CHIRINO, ARTHUR, J.;DESJARLAIS, JOHN, R.
发明人
MARSHALL, SHANNON, ALICIA;MOORE, GREGORY, L.;CHIRINO, ARTHUR, J.;DESJARLAIS, JOHN, R.
