SIGMA-2 RECEPTOR AGONISTS AND THEIR USE IN THE TREATMENT OF HIV INFECTION
摘要
The present invention relates to sigma-2 receptor agonists and their use in the treatment of immunodeficiency virus infections, especially human immunodeficiency virus (HIV) infections. The invention particularly relates to sigma-2 agonists, especially CB-184 and its analogues, that decrease cellular production of sphingomyelin when provided to recipient cells, and inhibit HIV replication.
申请公布号
WO2004064775(A3)
申请公布日期
2005.12.01
申请号
WO2004US00739
申请日期
2004.01.14
申请人
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE;CRAWFORD, KEITH, W.;BOWEN, WAYNE, D.;HILDRETH, JAMES, E.
发明人
CRAWFORD, KEITH, W.;BOWEN, WAYNE, D.;HILDRETH, JAMES, E.
