The invention relates to antigen-presenting cells having specificity against a selected antigen and methods for making the cells. The invention also relates to a method of selecting efficient antigen-presenting cells using reporter fusion constructs. The highly efficient antigen-presenting cells of the invention will provide a therapeutic strategy of modulating immune responses for a variety of diseases.
申请公布号
WO2005113589(A2)
申请公布日期
2005.12.01
申请号
WO2005US17343
申请日期
2005.05.18
申请人
DANA-FARBER CANCER INSTITUTE;HIRANO, NAOTO;BUTLER, MARCUS;NADLER, LEE, M.