发明名称 |
MODIFIED ANTIBODY |
摘要 |
<p>Recombinant antibody-based molecules that trigger both T-cell and B-cell immune responses are disclosed. The recombinant molecules are comprised by at least one targeting unit and at least one antigenic unit connected through a dimerization motif. Also disclosed are nucleic acid molecules encoding the recombinant antibody-based molecule and methods of treating multiple myeloma or lymphoma in a patient using the recombinant antibody-based molecules or the nucleic acid molecules.</p> |
申请公布号 |
EP1599504(A1) |
申请公布日期 |
2005.11.30 |
申请号 |
EP20040714520 |
申请日期 |
2004.02.25 |
申请人 |
MEDINNOVA AS |
发明人 |
BOGEN, BJARNE;FREDRIKSEN, AGNETE, BRUNSVIK;SANDLIE, INGER |
分类号 |
C07K16/46;C07K16/28;C07K16/44;C07K19/00 |
主分类号 |
C07K16/46 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|