A single-tube method and system for platelet function analysis

摘要

The present invention relates to a method for determining platelet activation. One method includes obtaining a baseline count of platelets in a sample comprising platelets in a liquid medium obtained from a physiological source of the platelets wherein the sample may include an anti-coagulant, adding a platelet activation agonist to the sample and after activation of activatable platelets in the sample, a count of unactivated platelets in the sample is then obtained and the difference between the baseline count of platelets and the count of unactivated platelets is determined. This difference is a measure of the activity of the platelets in the original sample. The present invention further relates to a kit for determining platelet activation.